This bill establishes a comprehensive prohibition on the Federal Government's involvement with human fetal tissue obtained from induced abortions. Specifically, no federal department, agency, or office may conduct, fund, approve, or otherwise support any research utilizing such tissue. This measure aims to prevent federal resources from being used in research activities that rely on tissue derived from induced abortions. The legislation explicitly permits research on human fetal tissue obtained after a miscarriage or stillbirth, provided it adheres to existing Public Health Service Act guidelines. It also allows for the development of **new, high-efficiency cell lines**, including for the production of vaccines, as long as these lines are not derived from human fetal tissue obtained from induced abortions. This distinction ensures that ethical alternatives for research and development are not restricted. Furthermore, the bill amends current law to prohibit the **solicitation or knowing acquisition, receipt, or acceptance** of donations of human fetal tissue if it was obtained pursuant to an induced abortion or if a human pregnancy was deliberately initiated to provide such tissue. These amendments to the Public Health Service Act reinforce the bill's core purpose by restricting the supply chain for such tissue in federally related activities.