The bill mandates the Secretary of Defense, in coordination with the Secretary of State, to establish a security cooperation initiative named the Partnership for Indo-Pacific Industrial Resilience Authorization Act . This initiative aims to strengthen cooperation among the defense industrial bases of the United States and its allies and partner countries in the Indo-Pacific region. Its primary objectives include enabling the production and supply of necessary materials for military forces, expanding industrial base capability and workforce, and enhancing supply chain security and resilience. The partnership also seeks to identify and mitigate industrial base vulnerabilities, advance research and development, and promote co-development and procurement collaboration in key defense sectors. To lead these efforts, the Secretary of Defense must designate a senior civilian official at the Assistant Secretary level or above within 180 days of enactment. The Secretary will also establish a process to determine participating allies and partners, including countries like Australia, Japan, and the Republic of Korea. The bill grants authorities to the Secretary to enter into agreements, establish working groups, provide technical assistance, and use appropriated funds for these purposes. Furthermore, the Secretary is required to submit annual reports to Congress on the Partnership's status and progress, including assessments of vulnerabilities and recommendations, with the authority for this initiative terminating on December 31, 2030.