This Senate Resolution declares that the Senate and the American people no longer have confidence in Secretary of Health and Human Services Robert Fitzgerald Kennedy Jr., and therefore he should be removed from his position. The resolution asserts that the Secretary has engaged in a pattern of conduct incompatible with his constitutional and statutory duties, including furthering an anti-science and anti-vaccine agenda by targeting and replacing scientists with unqualified associates, thereby undermining access to and trust in vaccines. The resolution details several failures, such as not meeting obligations to support health promotion, preventive services, and research for health disparities, particularly affecting women and minorities. It also highlights the Secretary's alleged unlawful reduction in force and reorganization of Department functions, which led to the termination of critical public health funding for states, jeopardizing disease surveillance and immunization programs. Furthermore, the resolution points to the abrupt termination of numerous research grants, including those for Alzheimer's and HIV prevention, often under the guise of eliminating projects related to "gender identity" or diversity, equity, and inclusion. The Secretary is accused of mass firings across various Department agencies, including the elimination of Offices of Minority Health and significant staff reductions at the Administration for Children and Families and the Administration for Community Living, impacting services for children, seniors, and individuals with disabilities. These actions have resulted in multiple lawsuits from states and health organizations, challenging the legality and impact of his directives. The resolution also notes the elimination of staff in Freedom of Information Act offices, hindering government transparency. A significant focus is placed on the Secretary's actions regarding vaccines, including the firing and replacement of the Advisory Committee on Immunization Practices (ACIP) members with vaccine skeptics, leading to a review of the childhood vaccine schedule. The resolution cites the Secretary's questioning of vaccine safety, halting of vaccine hesitancy research, and the cancellation of mRNA vaccine development projects. These actions, coupled with the resignation of high-level health officials and a multi-state measles outbreak, are presented as evidence of a deliberate effort to discredit science and erode public trust, ultimately jeopardizing American health and undermining the Department's mission.