The PRIME Meat Processing in Indian Country Act amends the Federal Meat Inspection Act to empower Indian Tribes and Tribal organizations to conduct their own meat inspections. It authorizes the Secretary of Agriculture to enter into self-determination contracts with these entities, allowing Tribal personnel to perform inspections at tribally-owned meat processing facilities. These contracts facilitate the hiring and training of Tribal inspectors, enabling greater self-governance in food safety. Inspections conducted under these contracts must meet federal standards, ensuring food safety and quality comparable to those for other federally inspected facilities. Tribal personnel are granted enforcement authority, including the ability to halt processing for uncorrected violations. Meat products inspected by Tribal personnel will bear a Federal inspection label and are authorized for sale in interstate commerce , though not foreign commerce. To support these efforts, the bill deems Tribal personnel as federal employees for purposes of the Federal Tort Claims Act and requires Tribes to maintain appropriate insurance, with a waiver of sovereign immunity to the extent of coverage. The Secretary is mandated to provide technical assistance and maintain oversight authority, including recall and audit powers. Additionally, Tribes operating under these contracts become eligible for USDA rural development loans and grants, fostering economic growth in Indian Country.