The PFAS Accountability Act of 2025 amends the Toxic Substances Control Act to establish a new federal cause of action for individuals significantly exposed to per- and polyfluoroalkyl substances (PFAS). This legislation aims to encourage PFAS research and provide accountability for irresponsible manufacturing and use of these substances. It seeks to address harm to exposed individuals by codifying their injury and shifting the costs of medical monitoring from them to the parties responsible for the exposure, while also providing incentives for industry to fund PFAS safety research. Under this Act, an individual significantly exposed to PFAS, or with reasonable grounds to suspect such exposure, may bring a claim in federal court against manufacturers who created the PFAS and foresaw or should have foreseen human exposure. Courts may award medical monitoring if the individual has been significantly exposed, faces an increased risk of developing a PFAS-associated disease, requires different or additional diagnostic medical examinations, and those examinations are effective. The bill establishes a presumption of significant exposure if PFAS were released into areas of exposure for at least one year or if testing detects PFAS in the individual's body, a presumption which defendants can rebut with independent testing at their own cost. Furthermore, courts are encouraged to promote independent research and may lower the standard for scientific proof regarding increased risk if toxicological data is insufficient, even ordering new studies. Importantly, this Act does not preempt existing state law claims or remedies.