This legislation, known as the Dennis John Benigno Traumatic Brain Injury Program Reauthorization Act of 2025, aims to reauthorize and enhance federal efforts concerning traumatic brain injury (TBI). It extends appropriations for the national TBI surveillance and registries program, as well as state grant programs, through fiscal year 2030, ensuring continued funding for critical initiatives. The bill significantly expands the scope of the National Program for Traumatic Brain Injury Surveillance and Registries . It mandates the collection of more detailed data on TBI incidence and prevalence, specifically focusing on populations at higher risk due to occupational or circumstantial factors, and identifying the causes and risk factors for TBI. The program will also gather information on short- and long-term outcomes, including related mental health and other conditions, and requires the public availability of aggregated TBI and concussion data, tailored to high-risk groups. Furthermore, the legislation modifies the State Grant Programs for TBI projects, requiring states to consider high-risk populations in outreach efforts and including Tribal entities. It introduces a maintenance of effort requirement for non-Federal expenditures and allows for waivers of up to 50 percent of matching funds under certain conditions. The bill also updates the definition of traumatic brain injury and allows the Secretary to revise it as needed. Finally, the Act mandates two key reports. The Secretary of Health and Human Services must submit a report to Congress within two years detailing an overview of high-risk TBI populations, CDC activities, outreach efforts, and associated challenges. Additionally, a comprehensive study is required on the incidence, prevalence, and long-term or chronic symptoms and conditions related to TBI, including correlations with other health issues and gaps in research, with its findings to be made publicly available.