The "Muslim Brotherhood Terrorist Designation Act of 2025" requires the President to designate the Muslim Brotherhood as a foreign terrorist organization (FTO) and impose related sanctions. This legislation aims to prohibit Muslim Brotherhood operations in the United States and restrict its members' entry. It also directs the Secretary of State to submit annual reports to Congress regarding the organization and its branches. The bill amends the Anti-Terrorism Act of 1987, adding the Muslim Brotherhood as a terrorist organization alongside the PLO. It includes new findings asserting Hamas is a Muslim Brotherhood branch, citing its FTO designation and its October 7, 2023, attack. Furthermore, the legislation mandates that any foreign person determined to be a Muslim Brotherhood member will be ineligible for visas, admission, or parole, and their current visas must be revoked. Within 90 days of enactment, the President must impose sanctions on the Muslim Brotherhood, including designation as an FTO or sanctions under Executive Order 13224. The Secretary of State is directed to annually identify all Muslim Brotherhood branches globally and assess whether their activities meet the criteria for FTO designation. Based on these determinations, the President must impose corresponding sanctions on these branches, with sanctions on the main organization remaining for at least four years.