The Youth Substance Use Prevention and Awareness Act aims to combat youth substance use by expanding a federal grant program. It amends the Omnibus Crime Control and Safe Streets Act of 1968 to allow grants for developing, implementing, or expanding research-based public service announcement campaigns specifically targeting youth substance use prevention. These campaigns must use age-appropriate materials across various platforms, including television, radio, print, outdoor, and digital media, and can also fund public service announcement contests that solicit submissions from youth. Furthermore, the bill mandates that the Attorney General publish an annual report on all grants awarded for these campaigns. This report must detail the grant and campaign, the research informing its development, any regional messaging, how it supports other prevention strategies, and an evaluation of its success , such as its effectiveness in reducing youth drug use.