The "Opioid Overdose Data Collection Enhancement Act" amends the Omnibus Crime Control and Safe Streets Act of 1968 to significantly enhance the Comprehensive Opioid Abuse Grant Program . Its primary purpose is to expand the adoption and implementation of advanced data collection tools, including mobile-friendly software, for tracking fatal and nonfatal overdoses. This initiative also focuses on monitoring the administration of opioid overdose reversal medication in near real-time, aiming for greater interoperability among various data systems. Under this enhanced program, States, local governments, coalitions of law enforcement agencies, and Indian tribes can develop and implement an Overdose Data Collection Program . These programs will track the locations of suspected overdoses and reversal medication use by first responders, supporting coordinated public safety and health responses. Grantees must ensure interoperability with existing data tools, make collected data available to relevant government entities, and conduct an audit of resources to prevent duplication when applying for grants.