This bill authorizes the National Guard to protect specific facilities and assets from unmanned aircraft systems (UAS). It amends the Homeland Security Act of 2002, along with titles 10 and 32 of the United States Code, to establish this new authority. The legislation enables the Secretary of Defense to authorize National Guard members to take actions against drones, provided certain conditions are met. Such authorization can be granted at the request of a State's chief executive officer for missions related to designated events, such as National Special Security Events. The bill also integrates the Department of Defense into the interagency coordination process for counter-UAS activities, requiring consultation with the Secretary of Defense before issuing guidance that might affect these operations. National Guard members must be ordered to duty under title 10 or 32 and assigned specific counter-UAS duties to be eligible for this expanded role.