This legislation aims to amend the Energy Policy Act of 2005 to bolster the development, demonstration, and commercial application of biotechnology products, thereby enhancing energy resiliency and strengthening supply chains. Congress recognizes that a significant barrier for U.S. biotechnology innovators is the challenge of scaling their products and processes to commercial viability, largely due to insufficient biomanufacturing capacity and infrastructure. To address these issues, the bill directs the Secretary of Energy to establish a minimum of two precommercial bioindustrial technology maturation facilities by September 30, 2030. These facilities will operate as user facilities, providing open access for governmental and nongovernmental entities to conduct research, development, and demonstration activities. Their primary goal is to "derisk" product and process technologies, facilitate the scaling of bioindustrial manufacturing, and support workforce development in the sector. The bill authorizes $225,500,000 for fiscal years 2026 through 2030 to carry out these provisions, emphasizing collaboration with various federal agencies, industry, and academia, and requiring a strategic plan for their implementation.