This bill mandates the National Institute of Standards and Technology (NIST) to facilitate the establishment of definitions, standards, resources, and frameworks within two years of enactment. The primary goal is to ensure that biological datasets generated from qualified federally funded research are "artificial intelligence-ready," meaning they are formatted to enable effective AI model training and support advancements in artificial intelligence and biotechnology. NIST is tasked with defining specific terms, including "artificial intelligence-ready," "biomanufacturing," "biotechnology," and "qualified federally funded research." The definition of qualified federally funded research will consider factors such as the amount of federal funding, the recipient's capability and expertise, and the size of the biological dataset. The legislation also requires NIST to establish data management resources and cybersecurity frameworks for federal departments and agencies, as well as for federally funded researchers who are collecting or generating biological datasets. These provisions are designed to ensure that the definitions, standards, resources, and frameworks are not overly burdensome on funding recipients. To guide this process, NIST must consult with various federal agencies, private sector entities, and academia, and establish an advisory group to provide recommendations. The bill also requires NIST to inventory existing biotechnology standards and biological datasets, making this information publicly available, and to conduct a test and evaluation of the established standards to assess their clarity and impact.