The "Full-Body Restraint Prohibition Act" aims to amend the Homeland Security Act of 2002 by adding a new section that strictly prohibits the Department of Homeland Security (DHS) from obligating federal funds for the acquisition of, or directly utilizing, full-body restraints. This prohibition applies to all DHS personnel, with a specific definition of "full-body restraints" as four-point and five-point restraints designed to immobilize an individual. A saving provision clarifies that the ban on acquisition does not apply to contracts or agreements entered into before the bill's enactment date. To ensure compliance, the bill mandates severe consequences for violations, requiring the removal from Federal service of any DHS officer or employee who violates the prohibition or deceives Congress or departmental leadership on related matters. Furthermore, the Secretary of Homeland Security must submit quarterly reports to specific congressional committees, detailing departmental compliance and an accounting of any full-body restraints in DHS possession. Should a violation of the utilization prohibition occur, these reports must include extensive information, such as the individual's demographics, the reason for restraint use, duration, any injuries sustained, and the identification of the responsible officer.