The "Enhancing Southbound Inspections to Combat Cartels Act" aims to significantly bolster the United States' capabilities for outbound inspections at its southern land border with Mexico. This legislation seeks to combat the smuggling of illicit goods, currency, and firearms by increasing resources and personnel dedicated to southbound inspections. It mandates a more robust approach to monitoring traffic leaving the U.S. to disrupt cartel operations and other illegal activities. To achieve these goals, the bill authorizes the Commissioner of U.S. Customs and Border Protection to acquire up to 50 additional non-intrusive imaging systems and supporting infrastructure, specifically for inspecting persons and conveyances traveling from the U.S. to Mexico. Furthermore, it directs the Director of U.S. Immigration and Customs Enforcement to hire at least 200 new Homeland Security Investigations special agents . These agents will primarily focus on investigating the smuggling of currency, firearms, contraband, and human trafficking from the United States into Mexico, as well as unauthorized entry into the U.S. The Act also establishes a minimum mandatory southbound inspection requirement , directing the Secretary of Homeland Security to ensure that by March 30, 2027, at least 10 percent of all conveyances traveling to Mexico are inspected. It requires the Secretary to submit a comprehensive report within one year detailing current inspection resources and future plans, including an assessment of Mexican government inspection capabilities. Additionally, the bill mandates quarterly reports from the CBP Commissioner on seizures of currency, firearms, and ammunition attempted to be trafficked out of the United States.