This bill provides for the relief of Luisa Mariana Sifuentes Arbirio, making her eligible for lawful permanent resident status in the United States. It specifically allows her to apply for an immigrant visa or adjustment of status, notwithstanding certain general provisions of the Immigration and Nationality Act. If she enters the United States before the specified deadline, she will be considered to have entered and remained lawfully, becoming eligible for adjustment of status as of the bill's enactment date, provided she files her application within two years. Furthermore, the legislation waives any existing grounds for her removal or denial of admission to the United States that are reflected in Department of Homeland Security or Department of State records. It mandates the rescission of any outstanding order of removal or finding of inadmissibility against her. Upon granting her permanent residence, one immigrant visa will be reduced from the total allocated to her country of birth, and her natural parents, brothers, and sisters will not receive any preferential immigration treatment based on their relationship to her.