This bill, known as the FACTS Act, aims to prevent synthetic opioid misuse and overdose among youth by establishing education partnership programs between public schools and public health agencies. It authorizes a pilot grant program for eligible partnerships to fund evidence-based activities focused on prevention, treatment, and recovery for secondary school-aged children. These activities include developing educational materials, professional development for staff, communication campaigns, and peer counseling, with priority given to areas with high youth illicit drug use. The bill establishes an Interagency Task Force to identify, evaluate, and recommend improvements for federal responses to youth synthetic opioid misuse, including developing a national strategy and identifying best practices. It also amends the Elementary and Secondary Education Act of 1965 to require professional development for school personnel on synthetic opioid dangers and mandates that local and state educational agency plans incorporate prevention strategies. To enhance data collection, the bill requires the National Center for Education Statistics to gather data on synthetic opioid access and its impact on school safety. It also mandates the inclusion of synthetic opioid questions in the Monitoring the Future and Youth Risk Behavior Survey , and allows school-based health centers to use funds for purchasing naloxone . Finally, it requires an evaluation of the State Unintentional Drug Overdose Reporting System to assess its effectiveness in tracking specific synthetic opioids.