This bill amends the Department of Energy Research and Innovation Act to establish a new program aimed at developing advanced fentanyl detection capabilities. It directs the Secretary of Energy to lead a comprehensive initiative for the research, development, testing, and evaluation of novel technologies. The core purpose is to create methods for rapidly detecting fentanyl vapor or particles in various critical environments. This program mandates coordination with the Attorney General, the Secretary of Homeland Security, and the Postmaster General to ensure a collaborative federal effort. These innovative technologies are specifically intended for rapid screening applications, including the inspection of mails , security within prisons , and surveillance at United States borders , alongside other related use cases to enhance public safety.