The Agent Orange Relief Act of 2025 seeks to address and remediate the ongoing health and environmental damage resulting from the use of Agent Orange during the Vietnam War. Findings indicate that millions of Vietnamese, Lao, Cambodian, and American individuals were exposed, leading to severe health issues and intergenerational effects, including birth defects and disabilities. The bill highlights a disparity in current Department of Veterans Affairs (VA) benefits, noting that while some conditions are recognized for U.S. veterans and birth defects for children of female veterans, similar recognition is lacking for Vietnamese Americans and most children of male U.S. veterans. To rectify these issues, the bill directs the VA to expand benefits for birth defects to all children of Vietnam veterans, irrespective of the veteran's gender, and mandates research into the intergenerational effects of Agent Orange exposure. Furthermore, it requires the Department of Health and Human Services (HHS) to conduct broad health assessments for Vietnamese Americans and their descendants, establishing centers to provide assessment, counseling, and treatment for Agent Orange-related conditions. Both Secretaries of HHS and VA are tasked with developing implementation plans within 180 days and providing quarterly reports to Congress on the progress of these provisions.