The Federal Firefighter Cancer Detection and Prevention Act of 2025 requires the Secretary of Defense to provide comprehensive, no-cost medical testing and related services to Department of Defense firefighters. These services are designed to detect, document, and prevent certain cancers, offered during annual health assessments or as clinically indicated. The bill outlines specific screening protocols for various cancers. For female firefighters, it mandates mammograms for breast cancer detection, with frequencies varying by age. Male firefighters are to receive information on prostate cancer screening risks and benefits, alongside prostate-specific antigen (PSA) tests , particularly for those over 50 or high-risk individuals over 40. Furthermore, the legislation includes provisions for colon cancer screening , offering communication about stool-based testing for those over 40 and visual examinations or stool-based tests for those over 45. It also requires routine screenings for any other cancers identified by the Centers for Disease Control and Prevention as having a higher incidence among firefighters. Firefighters retain the option to opt out of any provided medical testing or service. The Secretary is also tasked with documenting acceptance rates, test performance, and results to identify cancer occurrence trends, ensuring all personal information is anonymized before analysis and allowing for data sharing with the CDC to enhance understanding of firefighter cancer risks.