This bill, named the "Protect U.S. National Security Act," prohibits the use of federal funds to eliminate the United States Agency for International Development (USAID) as an independent establishment. It specifically bars funds from the American Relief Act, 2025, or any other appropriations, from being used for this purpose, aiming to safeguard USAID's critical role in U.S. foreign policy. The legislation includes a Sense of Congress asserting that any reforms to USAID should maintain United States soft power abroad and prevent adversaries from filling global voids. It further clarifies that only an act of Congress can eliminate USAID as an independent entity. To ensure compliance, the bill mandates that the Secretary of State annually certify adherence to this prohibition for five years.