The Partnerships for Better Health Act establishes a grant program, administered by the Secretary of Health and Human Services in consultation with the Secretary of Agriculture, to support integrated chronic disease prevention, management, and social support. These grants are specifically designed for underserved populations experiencing a high prevalence of chronic diseases. Lead eligible entities, which can include Federally qualified health centers or food banks, must submit applications detailing community needs, a care integration plan, and a framework for measurable outcomes. Priority for these grants will be given to applicants serving communities with high chronic disease prevalence, food insecurity, or those designated as health professional shortage areas, medically underserved, rural, or areas of persistent poverty. Grant funds can be used for various activities, including providing integrated care coordination, employing community health workers or patient navigators, offering nutrition and chronic disease education, and establishing or expanding Food Is Medicine programs . Funds also support data infrastructure upgrades, outcome evaluations, and outreach efforts to identify and engage eligible participants. Grant recipients must agree to use only evidence-based or evidence-informed models and serve populations with family incomes not exceeding 200 percent of the poverty line or those otherwise medically underserved. They must also ensure local coalition partners maintain agreements and participate in federal evaluations. Grantees are required to submit annual reports detailing program outcomes, participant demographics, services delivered, and lessons learned, specifically tracking reductions in HbA1c levels, blood pressure, and BMI, as well as changes in food security and healthcare utilization. A "lead eligible entity" applies on behalf of a "local coalition" which must include diverse partners such as clinical providers, food and nutrition organizations, public health departments, and community-based organizations. The term of a grant shall not exceed three years but may be renewed for an additional two-year period based on performance. The bill authorizes an appropriation of $15,000,000 for each of fiscal years 2027 through 2031 to fund these initiatives.