Bolstering Infectious Outbreaks Preparedness Workforce Act of 2021 or the BIO Preparedness Workforce Act of 2021 This bill establishes a student loan repayment program for health care and related professionals who are engaged in either bio-preparedness and response activities or infectious disease care in underserved communities. For each year that a professional meets the work requirements of the program, the Health Resources and Services Administration may pay up to $50,000 of the professional's student loan principal and interest, up to a maximum amount of $150,000.