Transparency to Rehabilitate United States Treaties with Mexico Act of 2021 or the TRUST with Mexico Act of 2021 This bill requires the Department of State to report on any nonconsensual use by Mexico of information or evidence obtained under the U.S.-Mexico Mutual Legal Assistance Treaty for purposes not stated in the request for such information or evidence. This report must encompass any such actions taken by Mexico on or after January 1, 2020, and it must include descriptions of (1) the action taken and its effect on U.S. national security, and (2) the assets and estimated net worth of Division General Salvador Cienfuegos Zepeda.