Deterring Enemy Forces and Enabling National Defenses Act of 2022 or the DEFEND Act of 2022 This bill requires the Department of Defense to seek to cooperate with Middle East allies and partners (i.e., countries of the Gulf Cooperation Council, Iraq, Israel, Jordan, Egypt, and other countries in the region as appropriate) to identify and develop an approach for such allies and partners to implement an integrated air and missile defense capability to protect against attacks from Iran and groups linked to Iran.