Coronavirus Vaccine and Therapeutic Development Act of 2021 This bill directs the Department of Health and Human Services (HHS) to increase the supply of vaccines and medical products that prevent or control COVID-19 (i.e., coronavirus disease 2019). To increase supplies, HHS must, as appropriate, award grants and enter other transactions to expand relevant research, procurement, and production activities. HHS must report to Congress on these actions. The report must assess and detail plans to enhance the supply chain and manufacturing capacity for the vaccines and products. It must also include plans to support domestic and international vaccination programs.