Investing in 21st Century Workforce Partnerships Act This bill requires the Department of Education (ED) to establish grant programs for educational or career training programs for students. First, ED must establish a career pathways innovation grant program. Under the program, ED must award grants to address the specialized skill needs of business and industry by carrying out programs that support career pathways in high school or career exploration in the middle grades. Second, ED must award grants for partnerships—between certain educational entities and employers—that provide educational or career training programs leading to recognized postsecondary credentials.