Save Our Seas 2.0: Enhanced Global Engagement to Combat Marine Debris Act This bill directs the Department of State and the President to make efforts to reduce marine debris. The State Department shall implement the U.S. policy to cooperate with foreign governments and the private sector to combat marine debris, which includes support for (1) strengthening systems for processing and reusing waste plastic, (2) developing and using reusable alternatives to disposable plastic products, and (3) deploying technology for capturing value from post-consumer materials and municipal solid waste streams. The President shall direct U.S. representatives to various international bodies to support U.S. marine debris policies. The Environmental Protection Agency is authorized to build partnerships in support such policies. The State Department shall report to Congress on the potential for entering into new agreements or creating a new forum to reduce land-based sources of marine debris and derelict fishing gear.