Advancing Emergency Preparedness Through One Health Act of 2018 This bill requires the Department of Health and Human Services and the Department of Agriculture, in coordination with other specified agencies and departments, to develop, publish, and submit to Congress a national One Health Framework for coordinated federal activities under the One Health Program, which encourages collaborative efforts to help better prevent, prepare for, and respond to zoonotic disease outbreaks. The framework must (1) describe existing efforts and contain recommendations for building upon and complementing the activities of federal entities; and (2) establish specified goals, including advancing the scientific understanding of the connections among human, animal, and environmental health.