To amend the Public Health Service Act to enhance the national strategy for combating and eliminating tuberculosis, and for other purposes.

Comprehensive TB Elimination Act of 2018 This bill amends the Public Health Service Act to reauthorize for FY2018-FY2023 and revise the tuberculosis (TB) prevention and treatment grant program administered by the Centers for Disease Control and Prevention. The Health Resources and Services Administration may also award grants to state and local governments and federally-qualified health centers for TB prevention and treatment efforts. Additionally, the Government Accountability Office must report on national TB prevention and treatment efforts.